Approach has potential to simplify generation of iPSCs for use in human stem cell therapies
Researchers at the University of California, San Diego School of Medicine report a simple, easily reproducible RNA-based method of generating human induced pluripotent stem cells (iPSCs) in the August 1 edition of Cell Stem Cell. Their approach has broad applicability for the successful production of iPSCs for use in human stem cell studies and eventual cell therapies. … Read the full story from the UCSD Newsroom
Four Department of Medicine researchers are coauthors of the study report in Cell Stem Cell:
- Neil Chi, MD, PhD, at right, assistant professor of medicine in the Division of Cardiology and member of the Institute for Genomic Medicine | Dr. Chi’s laboratory
- Dekker C. Deacon, graduate student in the Neil Chi laboratory
- Benjamin Yu MD, PhD, at right below, Health Sciences associate clinical professor in the Division of Dermatology and member of the Institute for Genomic Medicine | Dr. Yu’s laboratory
- Shantanu Kumar, PhD, postdoctoral fellow in the Benjamin Yu laboratory
Citation for the study report: Naohisa Yoshioka, Edwige Gros, Hai-Ri Li, Shantanu Kumar, Dekker C. Deacon, Cornelia Maron, Alysson R. Muotri, Neil C. Chi, Xiang-Dong Fu, Benjamin D. Yu, Steven F. Dowdy. Efficient Generation of Human iPSCs by a Synthetic Self-Replicative RNA. Cell Stem Cell – 1 August 2013 (Vol. 13, Issue 2, pp. 246-254) | Read the report